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Bioinformatic Workflows

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  • Genomics

  • Genome assembly
  • Variant analysis
  • Metagenomics
  • Genetic analysis

  • Transcriptomics

  • Exploratory gene expression analysis
  • RNA-seq analysis
  • Pathway analysis
  • Transcriptome assembly
  • Single-cell expression analysis
  • MicroRNA data analysis
  • Alternative splicing analysis
  • Fusion gene detection

    • Fusion gene detection

    Fusion genes generated by reshuffle of genetic material have been correlated with cancer progression and in the initial steps of tumorigenesis. Gene fusions occur due to the juxtapositioning of (parts of) two previously independent genes, giving rise to one or more hybrid genes, often as a product of somatic structural rearrangements. In RNA-seq, fusion genes can be identified through chimeric transcripts.

    Workflow

    Step 1

    Demultiplexing, quality control and filtering

    Step 2

    Alignment and detection of transcripts

    Step 3

    Filtering

    Available pipelines